An Organic Electrochemical Transistor to Monitor<i>Salmonella</i>Growth in Real‐Time

Organic electrochemical transistors (OECTs) are used in research and diagnostic applications due to their facile manufacture, scalability, biocompatibility. In these devices, the source–drain current upon gate voltage application depends on ion concentration electrolyte. This study investigates whether an OECT can be employed monitor bacterial growth since it is known that of charged species increases cultures during growth. A poly(3,4-ethylenedioxythiophene):polystyrene sulfonate-based single-well OECT, compatible with long-term incubation cultures, fabricated. It shown Salmonella alters transfer characteristics device demonstrates how applied real-time by recording at +0.5 V. The signal also measured filtrates devoid cells. suggests originates from metabolic products. Bacterial biofilm formation does not alter response. proof-of-principle presents recordings as alternative optical methods, allowing monitored transparent opaque media alike. By measuring products rather than cell multiplication, insight into stationary phase other nondividing states may obtained future.